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Enolate formation and electrophilic reactivity of acid derivatives Electrophilic reactivity very high high low very low Derivative acid chloride anhydride ester amide Structure O R Reactivity towards enolate formation very high R high low corex low R R Cl OO O O OEt NH2 O R In Chapter 21 we established that eno- lates can be formed from acid chlorides, but that they decompose to ketenes.
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Biochemistry 34:80058017 Precision and Uncertainties in Proton Therapy for Moving Targets 445 passive scattering.
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